Journal of Ageing, Disability and Chronic Disease – Current Issue

 

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  •                 Volume 1, Issue 1 J Ageing Disabil Chronic Dis 2017, 1:1

 

Alzheimer’s Disease and Cardiovascular Risk Factors, Review of Literature and Prospects of Future Research

Shoukry EE, M.D

Most of the patients with Alzheimer’s disease (AD) are found to have evidence of atherosclerotic cerebrovascular disease on autopsy. Cardiovascular risk factors including hypertension, diabetes mellitus and dyslipidemia are known risk factors for Alzheimer’s disease as well.

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Idiopathic Normal pressure Hydrocephalus. How Much Are We Missing

Shoukry EE, M.D

Normal pressure hydrocephalus (NPH) IS a type of brain malfunction caused by expansion of the lateral ventricles with distortion of the corona radiate fibers. The pathophysiology of idiopathic Normal pressure hydrocephalus remains unclear but is considered to be a communicating hydrocephalus due to reduced CSF absorption. It is theorized that shearing stress forces are exerted on periventricular vessels leading to ischemic changes or it is possibly secondary to interstitial edema with impaired blood flow. It was first described by Hakim and Adams in 1965 [1]. There are 2 types of NPH: Idiopathic (iNPH) and secondary to trauma, tumor, subarachnoid hemorrhage, meningitis…etc. [2]. Symptoms are summarized by Hakim’s triad of gait disorder, dementia and urinary incontinence or “Weird Walking Water”.

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